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Filtered Search Results
TARGETMOL CHEMICALS INC OBATOCLAX MESYLATE 25MG
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Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki 0.22 uM) and can induce apoptosis with up-regulation of Bim induced cytochrome c release and activation of caspase-3. purity: 99%
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TARGETMOL CHEMICALS INC VU6012962 10MG
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Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50 347 nM). purity: 98%
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Sigma Aldrich Fine Chemicals Biosciences Ciprofloxacin hydrochloride for peak identification European Pharmacopoeia (EP) Reference Standard | 86393-32-0 | MFCD00242856 |
Ciprofloxacin hydrochloride for peak identification European Pharmacopoeia (EP) Reference Standard | Mol Wt: 385.82 | 86393-32-0 | MFCD00242856 |
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000569606 MIDECAMYCIN-200MG
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Medchemexpress LLC Pleconaril | 153168-05-9 | 99.48% | 381.35 | 200 MG
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Pleconaril is a picornavirus capsid binding inhibitor that prevents attachment and/or virus uncoating. It has potential for use in research related to rhinoviruses and enteroviruses.
- Prevents attachment and/or virus uncoating
- For research use only
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Apexbio Technology LLC Batimastat (BB-94)(Synonyms: BB-94, Batimastat, MMP inhibitor BB-94), 1mg, CAS: 130370-60-4.
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Batimastat (BB-94 CAS 130370-60-4) is a synthetic small-molecule inhibitor targeting matrix metalloproteinases (MMPs) Structurally a polypeptide-like analogue of collagen substrates batimastat contains a peptidic backbone and a hydroxamate moiety that binds the catalytic zinc atom of MMPs It inhibits several MMP subtypes markedly including MMP-1 MMP-2 MMP-3 MMP-7 and MMP-9 with reported IC50 values of 3 4 20 6 and 4 nM respectively In preclinical studies batimastat demonstrates inhibitory effects on tumor growth and angiogenesis across various tumor models including ovarian and colon carcinoma xenografts making it relevant for cancer research and therapeutic development
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Medchemexpress LLC LED209 | 245342-14-7 | 98.4% | 383.49 | 200 MG
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LED209 is a potent and orally active small molecule inhibitor of the bacterial receptor QseC and a potent prodrug with high selectivity for QseC. It inhibits the binding of signaling molecules to QseC and exhibits antibacterial activity.
- Potent and orally active small molecule inhibitor of bacterial receptor QseC.
- Potent prodrug with high selectivity for QseC.
- Inhibits the binding of signaling molecules to QseC.
- Has antibacterial activity.
- Decreases biofilm formation in EAEC O104:H4 and multidrug-resistant clinical isolates of rUTIs.
- Reduces L. pneumophila replication.
- Protects mice against S. Typhimurium and F. tularensis murine infections.
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Medchemexpress LLC Romaciclib monohydrochloride | 2443816-41-7 | 99.3% | 450.60 | 25 MG
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Romaciclib monohydrochloride is an ATP-competitive and selective CDK8 inhibitor. It inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes with IC50s of 4.4 nM and 10.4 nM, respectively, and has a Kd of 3 nM for CDK8. It weakly inhibits CDK9 but shows no significant activity against CDK1, 2, 4, 6, 5, or 7. This compound inhibits phosphorylation of STAT1 S727 and STAT5 S726, demonstrating anti-tumor activity.
- ATP-competitive and selective CDK8 inhibitor.
- Inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes.
- Weakly inhibits CDK9 and shows no obvious activity against several other CDKs (CDK1, 2, 4, 6, 5, 7).
- Inhibits phosphorylation of STAT1 S727 and STAT5 S726.
- Possesses anti-tumor activity.
- Decreases IRF9 and STAT1 mRNA expression and mitogen-induced IER expression.
- Inhibits growth of AML tumors in a dose-dependent manner in SCID mice.
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Medchemexpress LLC 6PPD-quinone | 2754428-18-5 | 99.3% | 298.38 g/mol | C18H22N2O2 | 10 MG
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6PPD-quinone is an oxidized derivative of the tire antioxidant 6-PPD, supplied as a high-purity research reagent for environmental and toxicological studies. It is commonly used as a reference standard for analytical method development, quantification in environmental matrices, and mechanistic investigations of toxicity.
- High purity (99.3%).
- CAS number 2754428-18-5 for unambiguous identification.
- Suitable as an analytical reference standard for LC and GC methods.
- Intended for environmental and toxicological research applications.
- Available in milligram pack sizes for laboratory use.
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TARGETMOL CHEMICALS INC YKL-06-061 10MG
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Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3 respectively. purity: 99%
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000285818 QUINIDINE METHIODIDE 10MG
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eMolecules 957486-82-7 | Azido-PEG6-amine | ChemScene | MFCD03453240 | 350.416 | C14H30N4O6 | 97.000 | NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 1g | 632318428
Azido-PEG6-amine | ChemScene | 957486-82-7 | MFCD03453240 | 350.416 | C14H30N4O6 | 97.000 | NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 1g | 632318428
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TARGETMOL CHEMICALS INC SAFINAMIDE MESYLATE 25MG
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Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Safinamide mesylate (EMD 1195686 mesylate) a mesylate salt of Safinamide can reversibly and specifically inhibit MAO-B (IC50 98 nM) has 5918-fold selectivity against MAO-A. purity: 98%
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000567763 AZIDO-PEG2-C2-AMINE-250MG
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eMolecules 100517-53-1 | 3-Hydroxyquinoline-4-carbonitrile | Apollo Scientific | MFCD18415946 | 170.171 | C10H6N2O | 95.000 | Oc1cnc2ccccc2c1C#N | 250mg | 562447445
3-Hydroxyquinoline-4-carbonitrile | Apollo Scientific | 100517-53-1 | MFCD18415946 | 170.171 | C10H6N2O | 95.000 | Oc1cnc2ccccc2c1C#N | 250mg | 562447445
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